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Real Madrid vs Arsenal – UEFA Champions League: Start, team news, lineups

Title holders Real Madrid eye historic Champions League second leg comeback charge against Arsenal after 3-0 defeat in London.

Real Madrid players in action.
(From L) Real Madrid's #14 Aurelien Tchouameni, #09 Kylian Mbappe, #04 David Alaba, #16 Endrick and #05 Jude Bellingham attend a training session at Real Madrid Sports City in Valdebebas, Madrid on April 15, 2025, on the eve of the UEFA Champions League quarterfinal second leg between Real Madrid and Arsenal [Pierre-Philippe Marcou/AFP] (AFP)
Published On 15 Apr 2025

Who: Real Madrid vs Arsenal
What: UEFA Champions League quarterfinal, leg 2
Where: Santiago Bernabeu Stadium, Madrid
When: Wednesday at 9pm local time (19:00 GMT)

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Titleholder Real Madrid face a major hurdle in their quest for a seventh Champions League title in 12 seasons when they host Arsenal in the return leg of the quarterfinals on Wednesday.

The Gunners, winners of 13 English top-flight league titles, lead 3-0 after dismantling the reigning champions in London last week in the quarterfinal first leg.

Prevailing from a three-goal deficit to win the quarterfinal tie would be a step further than anything Los Blancos have managed so far, but with world-class offensive players like Kylian Mbappe and Vinicius Jr, Madrid still have a puncher’s chance of mounting a comeback against Arsenal on home soil at the Bernabeu.

Here is all to know before the blockbuster quarterfinal return leg between the winningest Champions League side (Real Madrid) and the most high-profile club in Europe to never win the trophy (Arsenal):

Have Real Madrid ever come back from a 3-0 deficit in the Champions League?

No. Madrid have mounted some memorable comebacks in the UEFA Champions League but have never overturned a 3-0 first-leg deficit in the tournament.

However, Madrid fans have some cause for optimism with the following statistics – the club has progressed from 14 of their last 15 Champions League knockout ties when playing the second leg at home.

How can Real Madrid beat Arsenal and progress to the semifinal?

Following on from their 3-0 first leg defeat to Arsenal at Emirates Stadium, Real Madrid can only complete a famous comeback and reach the semifinals if one of the following two scenarios plays out:

Whoever prevails from this quarterfinal will play either Paris Saint-Germain (PSG) or Aston Villa in the semis.

Soccer Football - Champions League - Quarter Final - First Leg - Arsenal v Real Madrid - Emirates Stadium, London, Britain - April 8, 2025 Arsenal's Declan Rice celebrates scoring their first goal with Jakub Kiwior REUTERS/Dylan Martinez
Arsenal’s Declan Rice, centre, was the hero in the first leg quarterfinal against Real Madrid, scoring two goals in their 3-0 victory on April 8, 2025, at Emirates Stadium in London, UK [Dylan Martinez/Reuters]

Team news

Real Madrid:

Arsenal:

Possible lineups

Real Madrid starting XI: Courtois; Vazquez, Rudiger, Asencio, Garcia; Valverde, Tchouameni; Rodrygo, Bellingham, Vinicius Jr; Mbappe.

Arsenal starting XI: Raya; Timber, Saliba, Kiwior, Lewis-Skelly; Odegaard, Partey, Rice; Saka, Merino, Martinelli.

Form guide

Arsenal:

With the 3-0 victory over Madrid last week, Arsenal extended their unbeaten streak to eight in European Cup/Champions League quarterfinal ties.

The Gunners did experience a letdown on Saturday, drawing 1-1 at home to mid-table Premier League side Brentford.

Arsenal results in their last five matches (across all competitions):

D-W-D-W-W (most recent result first)

Real Madrid:

The most successful Champions League team in history are still gunning for a treble (LaLiga, Copa del Rey, Champions League) in the 2024-25 season.

Madrid’s less-than-convincing 1-0 LaLiga win away to fourth-from-bottom Alaves on Sunday kept them in second spot on the ladder.

Real Madrid results in their last five matches (across all competitions):

W-L-L-D-W (most recent result first)

Player to watch: Mbappe

Real Madrid star forward Kylian Mbappe, 26, was sent off in the 38th minute for an ugly lunge in his side’s nervy victory against Alaves on Sunday. The unintended benefit of Mbappe’s early exit is that he should be fresh for Wednesday’s match against Arsenal.

Mbappe has 33 goals in 49 games across all competitions this season, matching Madrid’s all-time top goal scorer Cristiano Ronaldo’s tally in his first season at the club.

He failed to win the UEFA Champions League with PSG during his seven seasons at the club and is determined to win Europe’s most prestigious trophy for Los Blancos.

Kylian Mbappe reacts.
Kylian Mbappe’s #9 red card against Alaves on April 13, 2025, may have inadvertently given the Real Madrid star a much-needed rest before the return leg UEFA Champions League quarterfinal against Arsenal, to be played on Wednesday [Vincent West/Reuters]

Have Arsenal ever won the Champions League trophy?

Arsenal have never won the UEFA Champions League title.

They came closest in the 2005-06 season, losing the final to Barcelona 2-1.

Quote of the day

Vinicius Jr, Real Madrid: “Already thinking about Wednesday! We’re ready and looking forward to it. We’ll wait for you [Arsenal] at the Bernabeu and we’ll try everything. We are the Real! Hala Madrid.”